WYSOLONE 5MG contains Prednisolone which belongs to a group of medicines called Corticosteroids. It is used in the treatment of inflammatory and auto-immune conditions such as allergies (including severe allergic reactions), inflammation (affecting lungs including asthma, blood vessels heart, bowel/kidneys, muscles and joints including rheumatoid arthritis, eye/nervous system), skin conditions, infections and cancers (such as leukemia, lymphoma, and myeloma).
WYSOLONE 5MG is also used to prevent organ rejection after transplantation, and in cases to boost steroid levels when the body is unable to produce natural steroids on its own. It is also used to treat high calcium levels in the affected individuals which is generally characterized by symptoms such as stomach pain, nausea, bone pain, and muscle weakness.
WYSOLONE 5MG is not recommended for use in patients with fungal infections or in patients who have recently taken live vaccinations. Before taking WYSOLONE 5MG, inform your doctor if you have an infection, an underactive thyroid gland (hypothyroidism), seizures (fits), myasthenia gravis (muscle weakness), diabetes, high blood pressure, heart failure, liver or kidney disease.
WYSOLONE 5MG should be used with caution in pregnant and breastfeeding women. It is also used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking the medicine. The most common side effects of taking WYSOLONE 5MG are infection, signs of low potassium levels (such as constipation, fast heartbeat), signs of increased sugar in the blood and urine (such as increased thirst, frequent urination), high blood pressure, thinner skin, and impaired wound healing. Consult your doctor before taking the medicine.
USES OF WYSOLONE 5MG
- To treat inflammatory and auto-immune conditions such as:
- Allergies (including severe allergic reactions)
- Inflammation (affecting lungs including asthma, blood vessels & heart, bowel and kidney, muscles and joints including rheumatoid arthritis, eye/nervous system)
- Skin conditions, infections, and cancers (such as leukemia, lymphoma and myeloma)
- To prevent organ rejection after transplantation
- To boost steroid levels when the body is unable to make enough natural steroids on its own.
- To treat high calcium levels in the body
HOW WYSOLONE 5MG WORKS
Prednisolone works by blocking the production of polymorphonuclear leukocytes (immune cells responsible for inflammation and allergic reactions), which results in preventing the occurrence of inflammatory and allergic reactions in the affected individuals, thus treating the conditions.
DIRECTIONS FOR USE
Take WYSOLONE 5MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of WYSOLONE 5MG depending upon your age, body weight and disease conditions.
SIDE EFFECTS OF WYSOLONE 5MG
COMMON
- Infections such as tuberculosis
- Lower concentration of certain hormones, Cushing’s-like appearance, growth retardation in children
- Signs of low levels of potassium such as constipation, fast heartbeat, fatigue, muscle damage, muscle weakness or spasms
- Signs of high sodium levels such as confusion, muscle twitching, seizures, coma
- Signs of increased sugar in the blood and urine such as increased thirst, frequent urination, excessive hunger
- Osteoporosis (weak and brittle bones)
- Swelling due to fluid accumulation
- High blood pressure
- Thinner skin
- Impaired wound healing
- Muscle wasting
UNCOMMON
- Mental disorders (at high doses)
- Cataracts, glaucoma (increased eye pressure with pain)
RARE
- Depression
- Mania in patients without a history of psychiatric illness
- Increased benign pressure in the skull
- Breakdown of bone tissue
- Tendon rupture
Stop taking WYSOLONE 5MG and contact your doctor immediately if you experience any of the following side effects:
- Signs of severe allergic reaction (including angioedema) such as swelling of the face, tongue or throat, difficulty swallowing, hives and difficulty breathing, fever, drop in blood pressure
- Signs of pheochromocytoma crisis (rare, life-threatening adrenal gland tumor) such as anxiety, headache, palpitations, sweating, pale skin
- Signs of acute renal and kidney crisis (due to scleroderma) such as high blood pressure and decreased urine output
- Suicidal thoughts
- Exposure to people infected with chickenpox, shingles and measles
WARNING & PRECAUTIONS
PREGNANCY
WYSOLONE 5MG should be used with caution in pregnant women and in women planning for pregnancy. Consult your doctor before taking WYSOLONE 5MG.
BREASTFEEDING
WYSOLONE 5MG should be used with caution in breastfeeding women since the medicine may pass through milk. Consult your doctor before taking WYSOLONE 5MG.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience visual disturbance, dizziness or tiredness while taking WYSOLONE 5MG. Consult your doctor before taking this medicine.
KIDNEY
WYSOLONE 5MG should be used with caution in patients with kidney failure. Consult your doctor taking the medicine.
LIVER
WYSOLONE 5MG should be used with caution in patients with liver disease. Consult your doctor before taking WYSOLONE 5MG.
ALLERGY
Do not take WYSOLONE 5MG if you are allergic to Prednisolone or any other ingredient in this medicine.
HEART DISEASE
WYSOLONE 5MG should be used with caution in patients with heart disease such as heart failure. Consult your doctor before taking the medicine.
OTHERS
WYSOLONE 5MG is not recommended for use if you:
- Have fungal infection
- Recently had any live vaccinations
Before taking WYSOLONE 5MG, inform your doctor if you have:
- Or get an infection
- An underactive thyroid gland (hypothyroidism)
- Or had seizures
- Myasthenia gravis (muscle weakness)
- Or had been treated for tuberculosis
- Gastric, duodenal ulcer or inflammatory bowel disease such as ulcerative colitis, diverticulitis
- Diabetes
- High blood pressure
- Or had blood clots such as vein thrombosis
- Mood swings or psychotic tendencies
- Osteoporosis
- Adrenal tumor (pheochromocytoma)
- Surgically created new blood vessels or intestinal connections
- Scleroderma (rare auto immune disease characterized by chronic hardening and tightening of the skin)
- Intolerance to certain sugars such as lactose
Use in pediatrics:
WYSOLONE 5MG should be used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking it.
Use in geriatrics:
WYSOLONE 5MG should be taken with caution in elderly patients (above 65 years of age). Consult your doctor before taking it.
INTERACTIONS
A. Drug – Drug interactions:
- Rifampicin, isoniazid (medicines used to treat tuberculosis)
- Blood thinners like warfarin
- Carbamazepine, phenobarbital, phenytoin (medicines used to treat epilepsy)
- Anticholinergics (medicines used to treat Parkinson’s disease or asthma) Ex. trihexyphenidyl, benztropine, ipratropium, tiotropium.
- Cholinesterase inhibitors (medicines used to treat myasthenia gravis or Alzheimer’s disease) Ex. neostigmine, edrophonium
- Insulin (medicine used to treat diabetes)
- Anti-diabetic drugs (medicines used to treat diabetes) Ex. metformin, glipizide
- Cobicistat (medicine used to treat HIV infection)
- Estrogens (birth control pill used to prevent pregnancy)
- Acetylsalicylic acid and other non-steroidal anti-inflammatory medicines (used to treat pain and inflammation) Ex. paracetamol, ibuprofen
- Potassium lowering diuretics (medicines used to treat high blood pressure) such as thiazides (Ex. chlorothiazide, chlorthalidone), furosemide
- Medicines used to treat asthma such as xanthines (Ex. theophylline), beta-2 stimulants (Ex. salbutamol, terbutaline, salmeterol, formoterol)
- Amphotericin B (medicines used to treat fungal infection)
Overdosage:
If you or anyone else accidentally take too much of WYSOLONE 5MG, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Prednisolone |
| Pharmacological Category | : | Corticosteroids |
| Therapeutic Indication | : | Inflammatory & Auto-immune conditions, Organ rejection (after transplantation), Hypercalcemia |
| Dosage Forms | : | Tablet, Dispersible Tablet, Eye Drops, Ophthalmic Suspension, Oral Drops, Solution, Suspension, Syrup |
MORE INFORMATION
- Keep WYSOLONE 5MG out of reach of children
- Do not store WYSOLONE 5MG above 25°C
FAQs ABOUT WYSOLONE 5MG
What are the uses of WYSOLONE 5MG?
WYSOLONE 5MG is used to treat inflammatory and auto-immune conditions such as allergies, inflammation (affecting lungs, blood vessels & heart, bowel, kidneys, muscles, joints, eye or nervous system), skin conditions, infections and cancers (such as leukemia, lymphoma, and myeloma). It is also used to prevent organ rejection after transplantation, which is also indicated to boost steroid levels. It is also used to treat hypercalcemia, which is generally characterized symptoms such as stomach pain, nausea, bone pain and muscle weakness.
How does WYSOLONE 5MG work?
WYSOLONE 5MG works by blocking the production of polymorphonuclear leukocytes (immune cells responsible for inflammation and allergic reactions) which results in preventing the occurrence of inflammatory and allergic reactions in the affected individuals treating inflammatory and auto-immune conditions.
What side effects are seen with the use of WYSOLONE 5MG?
The most common side effects seen associated with the use of WYSOLONE 5MG are infections, signs of low potassium levels (such as constipation, fast heartbeat), signs of increased sugar in the blood and urine (such as increased thirst, frequent urination), high blood pressure, thinner skin, and impaired wound healing. Consult your doctor before taking the medicine.
Can WYSOLONE 5MG be used in pregnant and breast-feeding woman?
WYSOLONE 5MG should be used with caution during pregnancy and by women planning for pregnancy. It should also be used with caution in breastfeeding women as the medicine may pass through milk. Consult your doctor before taking the medicine.
Can WYSOLONE 5MG be given to children?
WYSOLONE 5MG should be used with caution in children and adolescents (below 18 years). Long term usage should be avoided. Your doctor will decide the dose, frequency and duration depending on the child’s age, body weight and disease conditions.
REFERENCES
1. KD. Tripathi. Corticosteroids. Essentials of medical pharmacology. Eighth 8th edition. 2013. Page – 313.
2. Yana Puckett; Aishah Gabbar; Abdullah A. Bokhari. Prednisone. NIH National Library of Medicin
e, National center for biotechnology information. StatePearls. May 2022. [Accessed on 9th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK534809/
3. Ciro Manzo, Jordi Serra-Mestres, Alberto Castagna, and Marco Isetta. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. August 2018. [Accessed on 9th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163472/
4. Accord UK Ltd. Electronic Medicines Compendium (EMC). [Revised on March 2021] [Accessed 9th July 2022] https://www.medicines.org.uk/emc/files/pil.5887.pdf
5. Healing Pharma India Pvt. Ltd. Predniheal 40. [Accessed on 9th July 2022] https://www.healingpharma.in/product/predniheal-40/
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